You can do this for multiple probes, simultaneously, and allow you to plan an entire insertion path right from your PC. When we set up that trajectory in simulation, then did a negative insertion, it let us find a place outside the brain that would be a safe start point for the insertion. ![]() But you can’t just go to that internal place in the brain, other than in a simulation. This simulation becomes even more valuable as you work with trajectory planning tools, allowing you to determine the probe’s insertion path, with the start and stop coordinates required for the probe’s trajectory to hit a target brain region.įor example, a researcher knew where he wanted to start and stop recording. Simulating an experiment helps you pre-determine all of your hardware settings, so you are not wasting time in the lab, arranging and then rearranging the hardware. This integration allows you to simulate, plan, execute, debug and repeat your experiments with greater ease and accuracy. ![]() Trajectory planning tools, such as Trajectory Explorer ( Peters Lab, University of Oxford) and Pinpoint ( Virtual Brain Lab), will allow the probe location to be available in a 3D brain model, visualizing the probe as insertions progress.ĭata acquisition apps, such as the Open Ephys GUI ( ), SpikeGLX ( ), and Allego ( ), will display the brain region and channel depth of each electrode on the real-time traces. This was the impetus behind the project, which we expect to deploy for beta testing in early 2023. “I know the region of the brain I want to explore, but how do I get there? And how will I know when I’m there?” As our key customers and mentors began to use the MPM hardware and VCS software, we began to receive questions about how they can better plan the trajectories of their silicon probes to target regions of the brain that they wish to explore. This can be done either in real time, or in simulation mode as you plan an experiment. Using our Pathfinder Software with Virtual Coordinate System (VCS), all probes move in a common stereotactic coordinate space. The MPM System allows you to automate and precisely place multiple silicon probes into one animal for acute in-vivo recording.
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